Last data update: May 13, 2024. (Total: 46773 publications since 2009)
Records 1-1 (of 1 Records) |
Query Trace: Phokasawad K[original query] |
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Monitoring HIV drug resistance: Early warning indicators to assess performance of Thailand's antiretroviral treatment program
Lertpiriyasuwat C , Teeraratkul A , Suchonwanich Y , Chatharojwong N , Phokasawad K , Yuktanon P , Pattarapayoon N , Bhakeecheep S , Bertagnolio S , Roels TH , Thanprasertsuk S . J Med Assoc Thai 2017 100 (9) 944-952 Objective: To describe trends in Thailand's antiretroviral treatment (ART) program performance assessed by HIV drug resistance early warning indicators (EWIs), as recommended by WHO, between 2009 and 2013. Material and Method: Seven EWIs were monitored, viral load (VL) testing coverage, VL suppression, retention in ART, lost to follow-up (LTFU), antiretrovirals (ARVs) dispensing practices, on-time pill pick-up, and pharmacy stock-outs. Data from ART adult patients in National Health Security Office Scheme were analyzed except for pharmacy stock-outs, which were reported from hospitals. Aggregated averages were calculated for each EWI. Chi-square for trend was applied to measure significant changes. Results: By September 2013, 174,284 adults were receiving ART at 929 hospitals. Over time, improvement in VL testing coverage (53.8% in 2009 to 79.8% in 2013) was observed. VL suppression and on-time pill pick up rates were well above 90%. Rates of retention in ART declined from 84.0 to 82.9%, whereas LTFU rates increased from 8.3 to 9.2% (p<0.001). Prescriptions with inappropriate ARVs decreased from 0.32 to 0.10% (p<0.001). Of reporting hospitals, 96.1%, 96.3%, and 96.2% observed no ARVs stock-out between 2011 and 2013. Conclusion: EWI is a useful tool to monitor ART program performance and to identify area where improvement is needed. |
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